compound introduction
Cyclo（-Pro-Val）是一种二酮哌嗪类化合物，具有抗真菌活性，也已从微生物和其他自然资源中分离出来。Cyclo（-Pro-Val）还能够激活或拮抗其他基于LuxR的群体感应系统。虽然Cyclo（-Pro-Val）的作用方式尚不清楚，但其活性表明细菌信号系统之间存在串扰。 Cyclo(-Pro-Val) is a diketopiperazines which shows antifungal activity, has also been isolated from microorganisms and further natural sources. Cyclo(-Pro-Val) is also capable of activating or antagonizing other LuxR-based quorum-sensing systems. While the mode of action of the cyclo(L-Pro-L-Val) is not known, its activity suggests the existence of cross talk among bacterial signaling systems.
