CAS number：1275582-97-2 molecular formula：C18H20Cl2N6O2
Ibezapolstat (ACX-362E) 是一种首创的DNA 聚合酶 IIIC ( DNA pol IIIC) 的抑制剂，被开发用于艰难梭菌感染 (CDI) 的研究。Ibezapolstat 具有广谱的抗艰难梭菌活性，在体外对临床分离的 104 种菌株作用的 MIC 范围为1-8 μg/mL。 Ibezapolstat (ACX-362E) is a first-in-class DNA polymerase IIIC (pol IIIC) inhibitor, with a Ki of 0.325 μM for the DNA pol IIIC from C. difficile. Ibezapolstat is developed for the research of C. difficile infection(CDI).
| Chinese alias | 伊贝扎波尔司他 | 伊贝泊司他 | ||
| English alias | 2-(((3,4-Dichlorophenyl)methyl)amino)-1,7-dihydro-7-(2-(4-morpholinyl)ethyl)-6H-purin-6-one | Ibezapolstat | D11791 | SCHEMBL15908884 | 2-(3,4-Dichloro-benzylamino)-7-(2-morpholin-4-yl-ethyl)-1,7-dihydro-purin-6-one | MS-27431 | 1275582-97-2 | Ibezapolsta | ||
| CAS number | 1275582-97-2 | molecular formula | C18H20Cl2N6O2 |
| molecular weight | 423.3 g/mol | Exact mass | - |
| PSA | 83.800 Ų | logp | 1.600 |
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