CAS number：1087243-14-8 molecular formula：C14H9ClN2O2
GRL-0496 是一种有效的氯吡啶酯衍生的 SARS-CoV 3CLpro 抑制剂，IC50 值为 30 nM。GRL-0496 显示出最佳的 SARS-CoV 抗病毒活性，EC50 值为 6.9 μM GRL-0496 is a potent chloropyridyl ester-derived SARS-CoV 3CLpro inhibitor, with an IC50 of 30 nM in both enzyme inhibitory and antiviral assays. GRL-0496 shows SARS-CoV antiviral activity, with an EC50 of 6.9 μM.
| Chinese alias | ALP-POS-c59291d4-5 | compound 10 | GRL0496 | ||
| English alias | 1H-Indole-4-carboxylic acid 5-chloro-3-pyridinyl ester | 5-Chloro-3-pyridinyl 1H-indole-4-carboxylate | GRL 0496 | ||
| CAS number | 1087243-14-8 | molecular formula | C14H9ClN2O2 |
| molecular weight | 272.69 g/mol | Exact mass | - |
| PSA | 55.000 Ų | logp | 2.800 |
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