PEAQX (NVP-AAM077) tetrasodium hydrate is a potent, selective and orally active NMDA antagonist, with IC 50 values of 270 nM and 29600 nM for hNMDAR 1A/2B and hNMDAR 1A/2B , respectively. IC50& Target:NMDA Receptor In Vitro:PEAQX (3 μM) produces similar caspase-3 activation, while NVP-AAM007 is approximately three-fold more potent. MCE has not independently confirmed the accuracy of these methods. They are for reference only. In Vivo:PEAQX (10-40mg/kg) dose-dependently increased cortical caspase-3 activity following sub-chronic administration. ? PEAQX (10 and 20mg/kg) shows enhanced locomotor activity in response to PCP challenge (4mg/kg on PN28-35) compared to saline pretrea Biological Activity:PEAQX (NVP-AAM077) tetrasodium hydrate is a potent, selective and orally active NMDA antagonist, with IC 50 values of 270 nM and 29600 nM for hNMDAR 1A/2B and hNMDAR 1A/2B , respectively.
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PEAQX tetrasodium hydrate
CAS number：unknown molecular formula：C17H15BrN3Na4O6P
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| Chinese alias | PEAQX 四钠水合物 | ||
| English alias | - | ||
| CAS number | unknown | molecular formula | C17H15BrN3Na4O6P |
| molecular weight | 560.15 g/mol | Exact mass | 10mM in Water |
| PSA | - | logp | - |
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