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6-Amino-5-((1S)-2,2-difluoro-4-(2-(4-(trifluoromethoxy)phenyl)acetyl)cyclopentyloxy)-N-methylnicotinamide

CAS number：1873373-33-1    molecular formula：C20H19F5N4O4

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overview

compound introduction

PF-06733804 是一种有效的pan-Trk抑制剂，抑制TrkA，TrkB和TrkC细胞，IC50分别为 8.4 nM，6.2 nM 和 2.2 nM。具有抗痛觉过敏作用。

Specs

Chinese alias-
English alias-
CAS number1873373-33-1molecular formulaC20H19F5N4O4
molecular weight474.38 g/molExact mass-
PSA107.000 Ųlogp2.500

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