PSB-KK1445 是一种强效且选择性的GPR18激动剂,对人和小鼠的 GPR18 的EC50分别为 45.4 nM 和 124 nM。PSB-KK1445 对两种 CB 受体亚型GPR55和 GPR183 的选择性均高出 200 倍以上。
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7-[(4-fluorophenyl)methyl]-8-{[2-(1H-indol-3-yl)ethyl]amino}-1,3-dimethyl-2,3,6,7-tetrahydro-1H-purine-2,6-dione
CAS number:885896-54-8 molecular formula:C24H23FN6O2
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| Chinese alias | - | ||
| English alias | - | ||
| CAS number | 885896-54-8 | molecular formula | C24H23FN6O2 |
| molecular weight | 446.5 g/mol | Exact mass | ≥99% |
| PSA | 86.300 Ų | logp | 3.700 |
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