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2-((3R,4S)-3-Fluoro-1-(2-(4-(trifluoromethoxy)phenyl)acetyl)piperidin-4-yloxy)-4-(2-hydroxy-2-methylpropoxy)benzamide

CAS number:1863905-38-7    molecular formula:C25H28F4N2O6

overview

compound introduction

PF-06737007 是一种有效的pan-Trk抑制剂,抑制TrkA,TrkB和TrkC细胞,IC50分别为 7.7 nM,15 nM 和 3.9 nM。具有抗痛觉过敏作用。

Specs

Chinese alias-
English alias-
CAS number1863905-38-7molecular formulaC25H28F4N2O6
molecular weight528.49 g/molExact mass≥99%
PSA111.000 Ųlogp3.600

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