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N-[2-(Dimethylamino)ethyl]-2-(1,1-dimethylethyl)-7-(4-fluorophenyl)-N-(phenylmethyl)-pyrazolo[1,5-a]pyrimidine-5-carboxamide

CAS number:1314206-29-5    molecular formula:C28H32FN5O

overview

compound introduction

RU-505 是一种有效的 β-淀粉样蛋白 (Aβ)-纤维蛋白原相互作用抑制剂,在荧光偏振 (FP) 和 AlphaLISA 测定中的IC50分别为 5.00 和 2.72 μM。RU-505 可透过血脑屏障。RU-505 可减少脑淀粉样血管病 (CAA)。RU-505可用于阿尔茨海默病 (AD) 的研究。

Specs

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English alias-
CAS number1314206-29-5molecular formulaC28H32FN5O
molecular weight473.6 g/molExact mass-
PSA53.700 Ųlogp5.100

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