RU-505 是一种有效的 β-淀粉样蛋白 (Aβ)-纤维蛋白原相互作用抑制剂,在荧光偏振 (FP) 和 AlphaLISA 测定中的IC50分别为 5.00 和 2.72 μM。RU-505 可透过血脑屏障。RU-505 可减少脑淀粉样血管病 (CAA)。RU-505可用于阿尔茨海默病 (AD) 的研究。
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N-[2-(Dimethylamino)ethyl]-2-(1,1-dimethylethyl)-7-(4-fluorophenyl)-N-(phenylmethyl)-pyrazolo[1,5-a]pyrimidine-5-carboxamide
CAS number:1314206-29-5 molecular formula:C28H32FN5O
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| Chinese alias | - | ||
| English alias | - | ||
| CAS number | 1314206-29-5 | molecular formula | C28H32FN5O |
| molecular weight | 473.6 g/mol | Exact mass | - |
| PSA | 53.700 Ų | logp | 5.100 |
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