CAS number：857531-00-1 molecular formula：C20H20ClN3
AT7867是ATP竞争性Akt1/2/3和p70S6K/PKA抑制剂，IC50分别为32 nM/17 nM/47 nM和85 nM/20 nM，对AGC激酶家族以外的蛋白几乎无活性。A potent ATP-competitive inhibitor of Akt1, Akt2 and Akt3 AT7867 is a potent ATP-competitive inhibitor of Akt1/2/3 and p70S6K/PKA with IC50 of 32 nM/17 nM/47 nM and 85 nM/20 nM, respectively; little activity outside the AGC kinase family. A potent ATP-competitive inhibitor of Akt1, Akt2 and Akt3
| Chinese alias | 4-(4-氯苯基)-4-[4-(1H-吡唑-4-基)苯基]哌啶 | ||
| English alias | 4-(4-(1H-pyrazol-4-yl)phenyl)-4-(4-chlorophenyl)piperidine | BDBM16219 | CHEBI:82708 | FT-0746989 | PS-3255 | SCHEMBL1977655 | EX-8670 | HMS3655A05 | NSC 61876 | SW219380-1 | J-513483 | A24956 | DTXSID00457772 | BP-12616 | NCGC00346549-06 | DB07859 | Q270 | ||
| CAS number | 857531-00-1 | molecular formula | C20H20ClN3 |
| molecular weight | 337.86 g/mol | Exact mass | ≥98% |
| PSA | 40.700 Ų | logp | 4.300 |
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