compound introduction
CGP60474 是一种高效的抗内毒素药物，是一种有效的细胞周期蛋白依赖激酶 (CDK) 抑制剂 (CDK1/B、CDK2/E、CDK2/a、CDK4/D、CDK5/p25、CDK7/H 和 CDK9/T 的 IC50 值分别为 26、3、4、216、10、200 和 13 nM)。CGP60474 是一种选择性和 ATP 竞争性 PKC 抑制剂。
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CGP60474
CAS number：164658-13-3 molecular formula：C18H18ClN5O
overview
Specs
| Chinese alias | - | ||
| English alias | 8II | BCP27893 | HMS3265E05 | GNF-Pf-88 | HY-11009 | Q27163218 | A910858 | cid_644215 | D97331 | HMS2218H05 | SCHEMBL1574530 | 3-[[4-[2-(3-chloroanilino)pyrimidin-4-yl]pyridin-2-yl]amino]propan-1-ol | CGP 60474 | SMR000463552 | 3-[[4-[2-[(3-Chlorophenyl)a | ||
| CAS number | 164658-13-3 | molecular formula | C18H18ClN5O |
| molecular weight | 355.82 g/mol | Exact mass | ≥99% |
| PSA | 83.000 Ų | logp | 3.800 |
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