PKCζ-IN-1 是一种抑制PKCζ和CDK2的化合物,显示出对PKCζ的IC50值为 5.18 nM,对CDK2的IC50值为 1.04 μM,具有显著的选择性,选择性比率达到 200 倍。PKCζ-IN-1 在抑制PKCζ的同时,还能减少CDK2的活性。
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4-{3-[7-(4-Methylpiperazin-1-Yl)-1h-Benzimidazol-2-Yl]-1h-Indazol-6-Yl}aniline
CAS number:1132609-87-0 molecular formula:
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| Chinese alias | - | ||
| English alias | - | ||
| CAS number | 1132609-87-0 | molecular formula | |
| molecular weight | 423.500 g/mol | Exact mass | ≥99% |
| PSA | 89.900 Ų | logp | 3.700 |
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