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4-{3-[7-(4-Methylpiperazin-1-Yl)-1h-Benzimidazol-2-Yl]-1h-Indazol-6-Yl}aniline

CAS number:1132609-87-0    molecular formula:

overview

compound introduction

PKCζ-IN-1 是一种抑制PKCζ和CDK2的化合物,显示出对PKCζ的IC50值为 5.18 nM,对CDK2的IC50值为 1.04 μM,具有显著的选择性,选择性比率达到 200 倍。PKCζ-IN-1 在抑制PKCζ的同时,还能减少CDK2的活性。

Specs

Chinese alias-
English alias-
CAS number1132609-87-0molecular formula
molecular weight423.500 g/molExact mass≥99%
PSA89.900 Ųlogp3.700

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