compound introduction
Barasertib (AZD1152) 是 Barasertib-hQPA 的前体药物，是高度选择性的 Aurora B 抑制剂，IC50 值为 0.37 nM。Barasertib (AZD1152) 可引起癌细胞生长阻滞和凋亡。
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AZD1152
CAS number：722543-31-9 molecular formula：C26H31FN7O6P
overview
Specs
| Chinese alias | 巴拉塞替 | ||
| English alias | 2-[ethyl-[3-[4-[[5-[2-(3-fluoroanilino)-2-oxoethyl]-1H-pyrazol-3-yl]amino]quinazolin-7-yl]oxypropyl]amino]ethyl dihydrogen phosphate | AZD1152 (Barasertib) | AC-35703 | CHEBI:167636 | AKOS040741193 | barasertibum | FT-0736007 | 2-(ETHYL(3-((4-((5-(2-((3-F | ||
| CAS number | 722543-31-9 | molecular formula | C26H31FN7O6P |
| molecular weight | 587.54 g/mol | Exact mass | - |
| PSA | 175.000 Ų | logp | -0.4 |
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