CAS number：79183-19-0 molecular formula：C15H9Cl2NO2
Apoptosis Activator 2强诱导caspase-3激活， PARP分裂， DNA断裂，导致细胞破坏(Apaf-1依赖性的)，IC50约为4 μM，抑制HMEC， PREC和MCF-10A细胞活性。An indoledione caspase activator Apoptosis Activator 2 strongly induces caspase-3 activation, PARP cleavage, and DNA fragmentation which leads to the destruction of cells (Apaf-1 dependent) with IC50 of ~4 μM, inactive to HMEC, PREC, or MCF-10A cells. An indoledione caspase activator
| Chinese alias | - | ||
| English alias | BCP06746 | Isatin-based compound, 16 | HB1293 | HY-18633 | 1H-Indole-2,3-dione, 1-((3,4-dichlorophenyl)methyl)- | BP-25394 | HSCI1_000276 | NCGC00025353-01 | SCHEMBL5426477 | SR-01000411093-2 | HMS3677G05 | Apoptosis Activator 2 | CBMicro_042945 | CHEBI:9 | ||
| CAS number | 79183-19-0 | molecular formula | C15H9Cl2NO2 |
| molecular weight | 306.14 g/mol | Exact mass | ≥98% |
| PSA | 37.400 Ų | logp | 3.600 |
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