CAS number：220904-83-6 molecular formula：C15H8Br2INO2
GW5074 已用作 C2 小鼠骨骼肌成肌细胞、 HT-29 结直肠腺癌细胞系和中性粒细胞中 cRaf1 的特异性抑制剂 GW 5074 is a potent and selective c-Raf inhibitor with IC50 of 9 nM, and has no effect on the activities of JNK1/2/3, MEK1, MKK6/7, CDK1/2, c-Src, p38 MAP, VEGFR2 or c-Fms
| Chinese alias | - | ||
| English alias | Q27077947 | (3Z)-3-[(3,5-dibromo-4-hydroxy-phenyl)methylene]-5-iodo-indolin-2-one | GW 5074 | Lopac0_000510 | 5-iodo-3-((3,5-dibromo-4-hydroxyphenyl)methylene)-2-indolinone | EC-000.2403 | NCGC00015478-01 | NCGC00015478-03 | 3-(3,5-Dibromo-4-hydroxy-benzy | ||
| CAS number | 220904-83-6 | molecular formula | C15H8Br2INO2 |
| molecular weight | 520.94 g/mol | Exact mass | - |
| PSA | 49.300 Ų | logp | 4.600 |
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