AR420626 是游离脂肪酸受体3 (FFAR3, GPR41) 的选择性激动剂,IC50为117 nM。AR420626 抑制尼古丁和 5-羟色胺诱导的大鼠结肠离体肌条运动的变化,并抑制 5-羟色胺诱导的大鼠排便。 product description: AR420626 is a selective agonist of free fatty acid receptor 3 (FFAR3, GPR41) with IC50 of 117 nM. AR420626 inhibits nicotine and serotonin-induced changes in motility of isolated muscle strips from rat colon and suppresses serotonin-induced fecal output in rats。
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AR 420626
CAS number:1798310-55-0 molecular formula:C21H18Cl2N2O3
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Specs
| Chinese alias | N-(2,5-二氯苯基)-4-(呋喃-2-基)-2-甲基-5-氧代-1,4,5,6,7,8-六氢喹啉-3-羧酰胺 | ||
| English alias | N-(2,5-Dichlorophenyl)-4-(furan-2-yl)-2-methyl-5-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carboxamide | AR420626 | ||
| CAS number | 1798310-55-0 | molecular formula | C21H18Cl2N2O3 |
| molecular weight | 417.29 g/mol | Exact mass | ≥98%(HPLC) |
| PSA | 71.300 Ų | logp | 3.800 |
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