CAS number：1088965-37-0 molecular formula：C32H38ClN5O4
GSK923295是首创的，特异的CENP-E驱动蛋白ATPase变构抑制剂，Ki为3.2 nM，对突变型I182和T183抑制活性较低。 GSK923295 is a first-in-class, specific allosteric inhibitor of CENP-E kinesin motor ATPase with Ki of 3.2 nM, and less potent to mutant I182 and T183. A specific allosteric inhibitor of CENP-E kinesin motor ATPase
| Chinese alias | - | ||
| English alias | NCGC00346943-01 | 3-Chloro-N-[(1S)-2-[[2-(dimethylamino)acetyl]amino]-1-[[4-[8-[(1S)-1-hydroxyethyl]imidazo[1,2-a]pyridin-2-yl]phenyl]methyl]ethyl]-4-(1-methylethoxy)-benzamide | 3-chloro-N-[(2S)-1-[[2-(dimethylamino)acetyl]amino]-3-[4-[8-[(1S)-1-hydroxye | ||
| CAS number | 1088965-37-0 | molecular formula | C32H38ClN5O4 |
| molecular weight | 592.14 g/mol | Exact mass | ≥98% |
| PSA | 108.000 Ų | logp | 5.000 |
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