compound introduction
MSN-125 is a potent Bax and Bak oligomerization inhibitor. MSN-125 prevents mitochondrial outer membrane permeabilization (MOMP) with an IC 50 of 4 μM. MSN-125 potently inhibits Bax/Bak-mediated apoptosis in HCT-116, BMK Cells, and primary cortical neurons, protects primary neurons against glutamate excitotoxicity In Vitro MSN-125 inhibits tBid/Bax-mediated MOMP in a concentration-dependent manner. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid IC50& Target:Bax Bak
