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1-Benzyl-4-(4-bromophenyl)-5-(3-imidazol-1-ylpropyl)-3-phenyl-4H-pyrrolo[3,4-c]pyrazol-6-one

CAS number:1542066-69-2    molecular formula:C30H26BrN5O

overview

compound introduction

p53-MDM2-IN-2 (Compound 5q) 是一种具有口服活性的p53-MDM2抑制剂,Ki值为 0.25 μM。p53-MDM2-IN-2 通过抑制NF-κB通路发挥抗肿瘤活性。

Specs

Chinese alias-
English alias-
CAS number1542066-69-2molecular formulaC30H26BrN5O
molecular weight552.46 g/molExact mass-
PSA56.000 Ųlogp5.300

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