SKLB325 是一种JMJD6抑制剂,其结合亲和力 (KD) 值为 0.755 μM,IC50值为 0.7797 μM。SKLB325 在体内外对卵巢癌具有抗肿瘤作用。SKLB325 诱导细胞凋亡 (apoptosis)。SKLB325 在肾细胞癌 (RCC) 中表现出显着的抗肿瘤功效。
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4-Hydroxy-2-(2-hydroxybenzylidenehydrazino)-6-methylpyrimidine
CAS number:66680-03-3 molecular formula:C12H12N4O2
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| Chinese alias | - | ||
| English alias | - | ||
| CAS number | 66680-03-3 | molecular formula | C12H12N4O2 |
| molecular weight | 244.250 g/mol | Exact mass | ≥99% |
| PSA | 86.100 Ų | logp | 0.800 |
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