CAS number：1615197-10-8 molecular formula：C20H18N6O3•HCl
BAY 61-3606 hydrochloride 是一种有效的，具有口服活性的，ATP 竞争性的，可逆的选择性Syk抑制剂，Ki为 7.5 nM，IC50为 10 nM。BAY 61-3606 hydrochloride 降低神经母细胞瘤细胞中的ERK1/2和Akt磷酸化。BAY 61-3606 hydrochloride 降低 K-rn 细胞裂解物中Syk磷酸化。BAY 61-3606 hydrochloride 作用于乳腺癌细胞，通过下调Mcl-1促进 TRAIL 诱导的细胞凋亡。
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| CAS number | 1615197-10-8 | molecular formula | C20H18N6O3•HCl |
| molecular weight | 390.403646 g/mol | Exact mass | ≥98% |
| PSA | 117.000 Ų | logp | - |
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