CAS number：635702-64-6 molecular formula：C21H23N7O2S·HCl
Pazopanib HCl (GW786034 HCl)是一种新型的针对VEGFR-1， VEGFR-2， VEGFR-3， PDGFR， FGFR， c-Kit和c-fms等多个靶点的抑制剂，IC50分别是10 nM， 30 nM， 47 nM， 84 nM， 74 nM， 140 nM和146 nM。A multi-targeted inhibitor. Pazopanib (GW786034) is a novel multi-target inhibitor of VEGFR1, VEGFR2, VEGFR3, PDGFR, FGFR, c-Kit and c-Fms with IC50 of 10 nM, 30 nM, 47 nM, 84 nM, 74 nM, 140 nM and 146 nM, respectively. A multi-targeted inhibitor.
| Chinese alias | 盐酸帕唑帕尼 | ||
| English alias | GW786034 HCl | 5-[[4-[(2,3-dimethylindazol-6-yl)-methylamino]pyrimidin-2-yl]amino]-2-methylbenzenesulfonamide;hydrochloride | pazopanib HCl | Pazopanib HCl (GW786034 HCl) | 5-((4-((2,3-Dimethyl-2H-indazol-6-yl)methylamino)pyrimidin-2-yl)amino)-2-methylben | ||
| CAS number | 635702-64-6 | molecular formula | C21H23N7O2S·HCl |
| molecular weight | 473.98 g/mol | Exact mass | ≥98% |
| PSA | 127.000 Ų | logp | - |
No numbering system information yet
No physical and chemical property information yet
No production method and use information yet
No upstream information yet
No downstream information yet
