Ac2-26 是 annexin 1 的 N 末端肽,具有抗炎活性。Ac2-26 通过伴侣介导的自噬 (CMA) 诱导溶酶体中 IKKβ 蛋白的减少。Ac2-26 可改善肺缺血再灌注损伤。Ac2-26 还可抑制哮喘大鼠模型的气道炎症和高反应性。
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Ac-Ala-Met-Val-Ser-Glu-Phe-Leu-Lys-Gln-Ala-Trp-Phe-Ile-Glu-Asn-Glu-Glu-Gln-Glu-Tyr-Val-Gln-Thr-Val-Lys-OH
CAS number:151988-33-9 molecular formula:C141H210N32O44S
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| Chinese alias | - | ||
| English alias | - | ||
| CAS number | 151988-33-9 | molecular formula | C141H210N32O44S |
| molecular weight | 3089.46 g/mol | Exact mass | ≥99% |
| PSA | 1280.000 Ų | logp | -8.500 |
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