CAS number：938069-71-7 molecular formula：C12H7BrO3S
CAY10526是通过选择性调节mPGES-1表达而抑制PGE2产生的物质。它剂量依赖性地抑制脂多糖刺激的RAW 264.7细胞中PGE2的产生，IC50值为1.8μM，而对COX-2表达没有任何影响。 CAY10526 is an inhibitor of PGE2 production through the selective modulation of mPGES-1 expression. It dose-dependently inhibits PGE2 production in lipopolysaccharide-stimulated RAW 264.7 cells with an IC50 value of 1.8 μM without any effect on COX-2 expression.
| Chinese alias | - | ||
| English alias | 3-(1-benzothiophen-2-yl)-4-bromo-2-hydroxy-2H-furan-5-one | 4-(Benzo[b]thiophen-2-yl)-3-bromo-5-hydroxyfuran-2(5H)-one | 4-Benzo[b]thien-2-yl-3-bromo-5-hydroxy-2(5H)-furanone | 4-Benzo[b]thiophen-2-yl-3-bromo-5-hydroxy-5H-furan-2-one | ||
| CAS number | 938069-71-7 | molecular formula | C12H7BrO3S |
| molecular weight | 311.15 g/mol | Exact mass | ≥98% |
| PSA | 74.800 Ų | logp | 2.800 |
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