compound introduction
TLR9-IN-1 is a potent and selective TLR9 inhibitor with an IC 50 value of 7 nM for human TLR9 . TLR9-IN-1 can be used for researching diseases associated with undesirable immune response In Vitro TLR9-IN-1 (compound no.29) (0-10 μM; 24 h) exhibits moderately inhibitory activity against IL-1b with an IC 50 of 1.61 μM in human monocytes (co-incubated with TLR8 agonist ORN8L, RNA oligonucleotide). MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid IC50& Target:human TLR9 7 nM (IC 50 )
