PD-1/PD-L1-IN 3 TFA, a macrocyclic peptide, is a potent and selective inhibitor of the PD-1/PD-L1 and CD80/PD-L1 interactions extracted from patent WO2014151634A1, compound No.1. PD-1/PD-L1-IN 3 TFA interferes with PD-L1 binding to PD-1 and CD80 by bindin Appearance:Solid IC50& Target:IC50: 5.60 nM (PD-1/PD-L1); 7.04 nM (CD80/PD-L1) In Vitro:PD-1/PD-L1-IN 3 (0.1 nM-10 μM) inhibits the binding of PD-1 and CD80 to PD-L1, with IC 50 s of 5.60 nM and 7.04 nM. PD-1/PD-L1-IN 3 blocks the binding of recombinant PD-L1-Ig to Jurkat-PD-1 cells, and also block binding of recombinant PD-1-Ig to eith Biological Activity:PD-1/PD-L1-IN 3 TFA, a macrocyclic peptide, is a potent and selective inhibitor of the PD-1/PD-L1 and CD80/PD-L1 interactions extracted from patent WO2014151634A1, compound No.1. PD-1/PD-L1-IN 3 TFA interferes with PD-L1 binding to PD-1 and CD80 by bindin
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PD-1/PD-L1-IN 3 TFA
CAS number：unknown molecular formula：C91H127F3N24O20S
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| Chinese alias | PD-1/PD-L1-IN 3 三氟乙酸 | ||
| English alias | - | ||
| CAS number | unknown | molecular formula | C91H127F3N24O20S |
| molecular weight | 1966.19 g/mol | Exact mass | ≥99% |
| PSA | - | logp | - |
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