BMSpep-57 hydrochloride is a potent and competitive macrocyclic peptide inhibitor of PD-1/PD-L1 interaction with an IC 50 of 7.68 nM. BMSpep-57 hydrochloride binds to PD-L1 with K d s of 19 nM and 19.88 nM in MST and SPR assays, respectively. BMSpep-57 hy Appearance:Solid IC50& Target:IC50: 7.68 nM (PD-1/PD-L1 interaction) In Vitro:In a ELISA competition assay, BMSpep-57 inhibits PD-1/PD-L1 binding up to 98.1% 300 nM. And it shows a concentration dependent inhibition of PD-1/PD-L1 binding with an IC 50 of 7.68 nM. BMSpep-57 induced high levels of IL-2 at 1 µM and 500 nM concent Biological Activity:BMSpep-57 hydrochloride is a potent and competitive macrocyclic peptide inhibitor of PD-1/PD-L1 interaction with an IC 50 of 7.68u2009nM. BMSpep-57 hydrochloride binds to PD-L1 with K d s of 19 nM and 19.88 nM in MST and SPR assays, respectively. BMSpep-5
All
Chemical Reagents
Biomedicine
Organic raw materials
Inorganic chemical industry
intermediate
Agricultural chemicals
Auxiliaries and catalysts
Fragrances and Flavors
Dyes and Pigments
Daily chemical industry
BMSpep-57 hydrochloride
CAS number：unknown molecular formula：C89H127ClN24O19S
overview
compound introduction
Specs
| Chinese alias | BMSpep-57 盐酸盐 | ||
| English alias | - | ||
| CAS number | unknown | molecular formula | C89H127ClN24O19S |
| molecular weight | 1904.63 g/mol | Exact mass | ≥99% |
| PSA | - | logp | - |
numbering system
No numbering system information yet
physicochemical properties
No physical and chemical property information yet
Safety information
No safety information yet
Production methods and uses
No production method and use information yet
Related
upstream information
No upstream information yet
downstream information
No downstream information yet
MSDS
Found 0 shareMSDS
