compound introduction
SR-717 free acid 是一种非核苷类STING激动剂，在 ISG-THP1 (WT) 和 ISG-THP1 cGAS KO (cGAS KO) 细胞中的EC50分别为 2.1 μM 和 2.2 μM。SR-717 free acid 是一种稳定的环鸟苷单磷酸腺苷单磷酸 (cGAMP) 类似物。具有抗肿瘤活性。
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4,5-difluoro-2-{[6-(1H-imidazol-1-yl)pyridazine-3-carbonyl]amino}benzoic acid
CAS number：2375420-34-9 molecular formula：C15H9F2N5O3
overview
Specs
| Chinese alias | - | ||
| English alias | - | ||
| CAS number | 2375420-34-9 | molecular formula | C15H9F2N5O3 |
| molecular weight | 345.26 g/mol | Exact mass | ≥98% |
| PSA | 110.000 Ų | logp | 1.400 |
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