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4-methyl-N-(naphthalen-1-yl)thiazol-2-amine

CAS number:1957-01-3    molecular formula:C14H12N2S

overview

compound introduction

CCR4 antagonist3 是一种有效的趋化因子受体 4 (CCR4) 拮抗剂,对 [125I]TARC (胸腺和活化调节趋化因子) 的IC50为 1.7 μM。CCR4 antagonist3 可抑制 CEM 细胞表面 [125I]TARC和巨噬细胞来源的趋化因子 (MDC) 与CCR4受体的结合。CCR4 antagonist3 也能在体外抑制 TARC 介导的 CEM 细胞迁移 (IC50=6.4 μM)。

Specs

Chinese alias-
English alias-
CAS number1957-01-3molecular formulaC14H12N2S
molecular weight240.33 g/molExact mass≥99%
PSA53.200 Ųlogp4.500

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