实际上,所有细胞花生四烯酸都在膜磷脂中被酯化,在那里它的存在通过多种相互连接的途径受到严格控制。游离花生四烯酸是类二十烷酸第二信使生物合成的瞬时关键底物。受体刺激的游离花生四烯酸的释放,代谢和再摄取是细胞信号转导以及炎症的每个重要方面。设计该化合物的目的是使花生四烯酸能够与蛋白质结合伴侣(例如脂肪酸结合蛋白(FABP))形成复合物。因此,它是用于阐明游离花生四烯酸的信号传导和转运的工具。 Virtually all cellular arachidonic acid is esterified in membrane phospholipids where its presence is tightly regulated through multiple interconnected pathways. Free arachidonic acid is a transient, critical substrate for the biosynthesis of eicosanoid second messengers. Receptor-stimulated release, metabolism, and re-uptake of free arachidonate are each important aspects of cell signalling, as well as inflammation. This compound was designed to allow arachidonic acid to be detected in complexes with protein binding partners such as fatty acid binding proteins (FABPs). It is thus a tool to be used in the general elucidation of the signaling and transport of free arachidonic acid.
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Arachidonic Acid-biotinamide
CAS number:1217901-28-4 molecular formula:C35H58N4O3S
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| Chinese alias | - | ||
| English alias | AKOS040756215 | Arachidonic Acid-biotinamide | Arachidonic acid-biotin | DTXSID901347575 | J-004682 | 1217901-28-4 | ||
| CAS number | 1217901-28-4 | molecular formula | C35H58N4O3S |
| molecular weight | 614.9 g/mol | Exact mass | A solution in ethano |
| PSA | - | logp | - |
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