RNA phosphoramidites, along with RNA CPG, and analogous to DNA synthesis support the synthesis of sequence-specific RNA oligonucleotides for RNA interference (RNAi) and can be used in target validation and other drug development techniques.Modern phosphoramidite-mediated synthesis has enabled routine high-yielding preparations of RNA oligonucleotides. High-quality RNA phosphoramidites are key to low failure rates, the high biological activity of synthesis products, and cost-effectiveness.Key Features Industry-standard 2′O-TBDMS protective group Consistent lot-to-lot purity and performance Compatible with deprotection methods based on methylamine or AMA Standard RNA phosphoramidites provide excellent coupling results whenused with ETT or BTT as an activator; best results are obtained withActivator 42 Capping with standard acetic anhydride capping reagent rather than withFast Deprotection Cap A Manufactured under a certified ISO 9001 quality systemDMT-2′O-TBDMS-rA(bz) Phosphoramidite is configured for MerMade Synthesizers.
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DMT-2′O-TBDMS-rA(bz) Phosphoramidite
CAS number：104992-55-4 molecular formula：C53H66N7O8PSi
overview
compound introduction
Specs
| Chinese alias | - | ||
| English alias | Adenosine, N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-[(1,1-dimethylethyl)dimethylsilyl]-, 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite] | PD158240 | SCHEMBL667192 | DMT-2'O-TBDMS-rA(bz) Pharmadite(R) | N-Benzoyl-5'-O-(4,4-Dimethoxyt | ||
| CAS number | 104992-55-4 | molecular formula | C53H66N7O8PSi |
| molecular weight | 988.19 g/mol | Exact mass | ≥97% |
| PSA | 164.000 Ų | logp | - |
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104992-55-4 | DMT-2′O-TBDMS-rA(bz) Phosphoramidite.pdf
