CAS number：850879-09-3 molecular formula：C23H21N5O3S
Amuvatinib (MP-470)是多靶点抑制剂，对c-Kit(D816H)，PDGFRα(V561D)和FLT3(D835Y)的IC50分别为10 nM，40 nM和81 nM。A multi-targeted tyrosine kinase inhibitor of PDGF and c-Kit。 Amuvatinib (MP-470) is a potent and multi-targeted inhibitor of c-Kit, PDGFRα and Flt3 with IC50 of 10 nM, 40 nM and 81 nM, respectively. A multi-targeted tyrosine kinase inhibitor of PDGF and c-Kit。
| Chinese alias | - | ||
| English alias | N-(benzo[d][1,3]dioxol-5-ylmethyl)-4-(benzofuro[3,2-d]pyrimidin-4-yl)piperazine-1-carbothioamide | NSC754349 | NSC-754349 | Amuvatinib [USAN] | Amuvatinib (MP-470, HPK 56) | BCPP000157 | DTXSID50234176 | N-(1,3-BENZODIOXOL-5-YLMETHYL)-4-(1)BENZOFURO(3,2-D | ||
| CAS number | 850879-09-3 | molecular formula | C23H21N5O3S |
| molecular weight | 447.52 g/mol | Exact mass | - |
| PSA | 108.000 Ų | logp | 3.5 |
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