compound introduction
IgG2是唯一通过胎盘的IgG亚类，其水平通常低于母亲体内的水平。IgG2的缺乏表明对细菌多糖的抗体反应较差，并可能导致对包囊细菌引起的感染的易感性增加。 由骨髓瘤血浆制备，经美国食品药品监督管理局要求的测试显示，骨髓瘤血浆对HBsAg、抗HCV、抗HBc无反应，对抗HIV 1和2呈阴性。 IgG2 is the only IgG subclass which passes through the placenta at a level generally lower than that found in the mother. A deficiency of IgG2 indicates a poor antibody response to bacterial polysaccharides and can lead to increased susceptibility to infections caused by encapsulated bacteria. Prepared from myeloma plasma shown to be non-reactive for HBsAg, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2 by FDA-required tests.
