IgE是血浆中含量最低的免疫球蛋白，其浓度低于正常血浆的0.6微克/毫升。在经历严重过敏反应和寄生虫感染的患者中发现IgE水平升高。在骨髓瘤的情况下，IgE是由单个浆细胞克隆产生的。然而，骨髓瘤IgE的结构是正常的，从骨髓瘤来源纯化的免疫球蛋白是研究免疫球蛋白行为的有用蛋白质。 Kappa由人骨髓瘤血浆制备，经美国食品药品监督管理局要求的测试显示，Kappa对HBsAg、抗HCV、抗HBc无反应，对抗HIV 1和2呈阴性。 产品引用： Pérez Ruiz, Elena, Marijn Kemper, Dragana Spasic, Ann Gils, Leo J. van IJzendoorn, Jeroen Lammertyn, and Menno WJ Prins. "Probing the Force-induced Dissociation of Aptamer-Protein Complexes." Analytical chemistry(2014). Pérez-Ruiz E, Lammertyn J, Spasic D. Evaluation of different strategies for magnetic particle functionalization with DNA aptamers. N Biotechnol.2016 Dec 25;33(6):755-762. doi: 10.1016/j.nbt.2016.06.1459. Epub 2016 Jun 16. Arghir J, et al. Improved surface plasmon resonance biosensing using silanized optical fibers. Sensors and Actuators B: Chemical, volume 216 September 2015 pg 518-526. Ref: Ishiaka, K. 1985. Methods Enzymol. 116, 76. IgE is the least abundant immunoglobulin in plasma, found at a concentration of less that 0.6 micrograms/ml of normal plasma. Elevated IgE levels are found in patients experiencing severe allergic reactions and parasitic infections. In a myeloma condition, IgE is produced by a single clone of plasma cells. The structure of myeloma IgE, however, is normal, and the immunoglobulin purified from a myeloma source is a useful protein for studying immunoglobulin behavior. Prepared from human myeloma plasma, Kappa shown to be non reactive for HBsAg, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2 by FDA-required tests. Product Citations: Pérez Ruiz, Elena, Marijn Kemper, Dragana Spasic, Ann Gils, Leo J. van IJzendoorn, Jeroen Lammertyn, and Menno WJ Prins. "Probing the Force-induced Dissociation of Aptamer-Protein Complexes." Analytical chemistry(2014). Pérez-Ruiz E, Lammertyn J, Spasic D. Evaluation of different strategies for magnetic particle functionalization with DNA aptamers. N Biotechnol.2016 Dec 25;33(6):755-762. doi: 10.1016/j.nbt.2016.06.1459. Epub 2016 Jun 16. Arghir J, et al. Improved surface plasmon resonance biosensing using silanized optical fibers. Sensors and Actuators B: Chemical, volume 216 September 2015 pg 518-526. Ref: Ishiaka, K. 1985. Methods Enzymol. 116, 76.
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免疫球蛋白E(IgE),人骨髓瘤血浆,Kappa
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| Chinese alias | - | ||
| English alias | - | ||
| CAS number | unknown | molecular formula | |
| molecular weight | - | Exact mass | ≥95%(SDS-PAGE) |
| PSA | - | logp | - |
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