Adenosine receptor antagonist 2 is an orally active A2a/A2b adenosine receptor antagonist with IC 50 s of 1 nM and 3 nM, respectively. Adenosine receptor antagonist 2 has anti-tumor activity In Vivo Adenosine receptor antagonist 2 (compound L-1; po; 10, 30, 100 mg/kg; twice a day for 22 days) inhibits tumor growth in female C57BL / 6mice mice with MC38(#22)-hpd-L1 cells . Adenosine receptor antagonist 2 (iv; 2 mg/kg) has a CLz of 14.7 mL/min·kg and an AUC of 2252 h·ng/mL. Adenosine receptor antagonist 2 (po; 10 mg/kg) has a C max of 8730 ng/mL in adult male ICR mice (weight 25-40g) . MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid IC50& Target:A2a adenosine receptor 1 nM (IC 50 ) A2b adenosine receptor 3 nM (IC 50 )
All
Chemical Reagents
Biomedicine
Organic raw materials
Inorganic chemical industry
intermediate
Agricultural chemicals
Auxiliaries and catalysts
Fragrances and Flavors
Dyes and Pigments
Daily chemical industry
Adenosine receptor antagonist 2
CAS number：2703054-47-9 molecular formula：C23H21FN8O
overview
compound introduction
Specs
| Chinese alias | 腺苷受体拮抗剂 2 | ||
| English alias | - | ||
| CAS number | 2703054-47-9 | molecular formula | C23H21FN8O |
| molecular weight | 444.46 g/mol | Exact mass | ≥99% |
| PSA | - | logp | - |
numbering system
No numbering system information yet
physicochemical properties
No physical and chemical property information yet
Safety information
No safety information yet
Production methods and uses
No production method and use information yet
Related
upstream information
No upstream information yet
downstream information
No downstream information yet
MSDS
Found 0 shareMSDS
