compound introduction
HHS-0701, a sulfur-triazole exchange (SuTEx) ligand, is a potent tyrosine-reactive prostaglandin reductase 2 (PTGR2) inhibitor. HHS-0701 blocks PTGR2 metabolism of the lipid substrate 15-Keto-PGE2. In Vitro HHS-0701 (0.1, 0.25, 0.5, 1, 2.5, 5, 10, 25 μM; 2 hours) results concentration-dependent blockade of probe labeling in treatment of recombinant PTGR2 overexpressing HEK293T cells. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid
