Eltanexor Z-isomer (KPT-8602 Z-isomer) is the less active isomer of KPT-8602. KPT-8602 is a potent CRM1 inhibitor.IC50:In Vitro: Eltanexor Z-isomer exhibits different inhibitory effects on Z138, MM15, 3T3 cell lines, with IC 50 s of 100 nM-50 μM, 30 μM, respectively.In Vivo: Form:Solid
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Eltanexor Z-isomer
CAS number:1642300-78-4 molecular formula:C17H10F6N6O
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Specs
| Chinese alias | Eltanexor Z-异构体 | ||
| English alias | - | ||
| CAS number | 1642300-78-4 | molecular formula | C17H10F6N6O |
| molecular weight | 428.29 g/mol | Exact mass | ≥96% |
| PSA | 99.600 Ų | logp | 2.500 |
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