KDM5-C49 (KDOAM-20) hydrochloride is a potent and selective inhibitor of KDM5 demethylases , with IC 50 s of 40 nM, 160 nM, and 100 nM for KDM5A , KDM5B , and KDM5C enzymes , respectively. KDM5-C49 hydrochloride can be used for the research of cancer Appearance:Solid-liquid mixture In Vitro:KDM5-C49 hydrochloride display poor permeability. Convert the carboxylate group of KDM5-C49 into an ethyl ester, to get a cell-permeable prodrug (KDM5-C70). MCE has not independently confirmed the accuracy of these methods. They are for reference onl Biological Activity:KDM5-C49 (KDOAM-20) hydrochloride is a potent and selective inhibitor of KDM5 demethylases , with IC 50 s of 40 nM, 160 nM, and 100 nM for KDM5A , KDM5B , and KDM5C enzymes , respectively. KDM5-C49 hydrochloride can be used for the research of cancer
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KDM5-C49 hydrochloride
CAS number：unknown molecular formula：C15H25ClN4O3
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| Chinese alias | KDM5-C49盐酸盐 | ||
| English alias | - | ||
| CAS number | unknown | molecular formula | C15H25ClN4O3 |
| molecular weight | 344.84 g/mol | Exact mass | ≥99% |
| PSA | - | logp | - |
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