Orexin A (Hypocretin-1) (human, rat, mouse) acetate is a hypothalamic neuropeptide with analgesic properties (crosses the blood-brain barrier). Orexin A (human, rat, mouse) acetate is also an OX1R agonist that induces the expression of BDNF and TH protein Appearance:Solid In Vitro:Orexin A (human, rat, mouse) acetate (0.1, 1, 10, 100 nM; 24 h) increases the expression of BDNF in SH-SY5Y human dopaminergic neuroblastoma cells in a dose-dependent manner. Orexin A (human, rat, mouse) acetate (1 nM; 1, 3, 6, 12, 24 h) increases th In Vivo:Orexin A (human, rat, mouse) acetate (300 ng/mouse; i.c.v.; single daily for 8 days) attenuates the loss of dopaminergic neurons and the decrease of tyrosine hydroxylase (TH) expression in the substantia nigra, normalized the striatal dopaminergic fibers, Biological Activity:Orexin A (Hypocretin-1) (human, rat, mouse) acetate is a hypothalamic neuropeptide with analgesic properties (crosses the blood-brain barrier). Orexin A (human, rat, mouse) acetate is also an OX1R agonist that induces the expression of BDNF and TH protein
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Orexin A (human, rat, mouse) (acetate)
CAS number：unknown molecular formula：C152H243N47O44S4.xC2H4O2
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| Chinese alias | Orexin A(人、大鼠、小鼠)(醋酸盐) | ||
| English alias | - | ||
| CAS number | unknown | molecular formula | C152H243N47O44S4.xC2H4O2 |
| molecular weight | - | Exact mass | ≥99% |
| PSA | - | logp | - |
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