AChE/BChE-IN-10 (Compound 7b) is a potent dual AChE and BChE inhibitor with IC 50 values of 0.176, and 0.47 μM, respectively. AChE/BChE-IN-10 shows good blood brain barrier permeability. AChE/BChE-IN-10 can inhibit Aβ-aggregation and be used in Alzheimer’ Appearance:Solid IC50& Target:AChE 0.176 μM (IC 50 ) BChE 0.47 μM (IC 50 ) In Vitro:AChE/BChE-IN-10 inhibits AChE in a non-competitive manner with K i of 0.21 μM, and BChE in a mixed-fashion with K i of 0.15 μM. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Biological Activity:AChE/BChE-IN-10 (Compound 7b) is a potent dual AChE and BChE inhibitor with IC 50 values of 0.176, and 0.47 μM, respectively. AChE/BChE-IN-10 shows good blood brain barrier permeability. AChE/BChE-IN-10 can inhibit Aβ-aggregation and be used in Alzheimer’
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AChE/BChE-IN-10
CAS number：unknown molecular formula：C26H30N2O2
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Specs
| Chinese alias | - | ||
| English alias | - | ||
| CAS number | unknown | molecular formula | C26H30N2O2 |
| molecular weight | 402.53 g/mol | Exact mass | ≥99% |
| PSA | - | logp | - |
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