compound introduction
PARP10/15-IN-3 (Compound 8a) is a potent PARP10 and PARP15 dual inhibitor with IC 50 values of 0.14 µM and 0.40 µM against PARP10 and PARP15 , respectively. PARP10/15-IN-3 is able to enter cells and rescue cells from apoptosis. Appearance:Solid IC50& Target:PARP10 0.14 μM (IC 50 ) PARP15 0.40 μM (IC 50 ) Biological Activity:PARP10/15-IN-3 (Compound 8a) is a potent PARP10 and PARP15 dual inhibitor with IC 50 values of 0.14 µM and 0.40 µM against PARP10 and PARP15 , respectively. PARP10/15-IN-3 is able to enter cells and rescue cells from apoptosis.
