compound introduction
EBNA1-IN-SC7 (compound SC7) is a selective Epstein-Barr nuclear antigen 1 ( EBNA1 ) inhibitor that interferes with EBNA1-DNA binding activity with an IC 50 value of 23 μM. EBNA1-IN-SC7 is used in EBV (Epstein-Barr virus)-related cancer research. In Vitro EBNA1-IN-SC7 (compound SC7) (5 µM) can completely block transcriptional activation of EBNA1 and show a 60% inhibition of Zta (EBV-encoded b-zip DNA binding protein) trans-activation in HEK293T cells. EBNA1-IN-SC7 (compound SC7) (10 µM, 6 days) has no significant effect on EBV genome copy number of Raji Burkitt lymphoma cells. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid
