Fradafiban (BIBU-52) hydrochloride is a nonpeptide platelet glycoprotein IIb/IIIa antagonist, which binds to the human platelet GP IIb/IIIa complex with a K d value of 148 nM. Appearance:Solid IC50& Target:Kd: 148 nM (human platelet GP IIb/IIIa complex) In Vitro:Fradafiban hydrochloride is a nonpeptide mimetic of the arginine-glycine-aspartic acid recognition sequence. Fradafiban hydrochloride binds with high affinity and selectivity to the human platelet GP IIb/IIIa complex and potently inhibits human platelet a In Vivo:Fradafiban hydrochloride has only very limited oral activity probably due to its high polarity and thus poor absorption after oral ingestion. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Biological Activity:Fradafiban (BIBU-52) hydrochloride is a nonpeptide platelet glycoprotein IIb/IIIa antagonist, which binds to the human platelet GP IIb/IIIa complex with a K d value of 148 nM.
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Fradafiban hydrochloride
CAS number：unknown molecular formula：C20H22ClN3O4
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| Chinese alias | 盐酸弗拉达非班 | ||
| English alias | - | ||
| CAS number | unknown | molecular formula | C20H22ClN3O4 |
| molecular weight | 403.86 g/mol | Exact mass | ≥99% |
| PSA | - | logp | - |
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