IL-4-inhibitor-1 (compound 52) is an IL-4 inhibitor, with an EC 50 of 1.81 µM In Vitro IL-4-inhibitor-1 (compound 52) displays low micromolar affinity and exhibits functional disruption of type II IL-4 binding in a cellular context. IL-4-inhibitor-1 (compound 52) exhibits dose-dependent reduction in pSTAT-6 levels with an EC 50 value of 3.1 µM, but did not affect the levels of STAT-6. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid IC50& Target:EC50: 1.81 µM (IL-4)
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IL-4-inhibitor-1
CAS number:1332184-63-0 molecular formula:C18H12FN3O2
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| Chinese alias | IL-4-抑制剂-1 | ||
| English alias | - | ||
| CAS number | 1332184-63-0 | molecular formula | C18H12FN3O2 |
| molecular weight | 321.31 g/mol | Exact mass | ≥98% |
| PSA | 103.000 Ų | logp | 3.500 |
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