Lumiracoxib是一种新型,选择性的COX-2抑制剂,IC50和Ki分别为0.14 μM和0.06 μM,比作用于COX-1选择性高515倍。A Cox-2 selective inhibitor and NSAID. Lumiracoxib is a novel, selective COX-2 inhibitor with IC50 and Ki of 0.14 μM and 0.06 μM, exhibits 515-fold selectivity over COX-1. A Cox-2 selective inhibitor and NSAID.
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Lumiracoxib
CAS number:220991-20-8 molecular formula:C15H13ClFNO2
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| Chinese alias | 罗美昔布 | ||
| English alias | {2-[(2-chloro-6-fluorophenyl)amino]-5-methylphenyl}acetic acid | BL164650 | 2-(2-(2-chloro-6-fluorophenylamino)-5-methylphenyl)acetic acid | AI3-37711 | 2-((2-Chloro-6-fluorophenyl)amino)-5-methylbenzeneacetic acid | Prexige | CHEBI:73044 | HMS3264F19 | S | ||
| CAS number | 220991-20-8 | molecular formula | C15H13ClFNO2 |
| molecular weight | 293.72 g/mol | Exact mass | - |
| PSA | 49.300 Ų | logp | 4.2 |
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