CAS number：301692-76-2 molecular formula：C18H16FNO4S
帕马考昔是一流的 NSAID 候选药物，是碳酸酐酶 (CA) 和 COX-2 的双重抑制剂。它在小鼠模型中抑制大肠腺瘤和肿瘤生长。 Polmacoxib is a first-in-class NSAID drug candidate, is a dual inhibitor of carbonic anhydrase (CA) and COX-2. Polmacoxib inhibits premalignant and malignant colorectal lesions in mouse models, partly through inhibiting tumor cell proliferation.
| Chinese alias | 4-(3-(3-氟苯基)-5,5-二甲基-4-氧代-4,5-二氢呋喃-2-基)苯磺酰胺 | 泊马昔布 | ||
| English alias | CG100649 | CG-100649 | CG 100649 | 4-[3-(3-fluorophenyl)-4,5-dihydro-5,5-dimethyl-4-oxo-2-furanyl]-benzenesulfonamide | ||
| CAS number | 301692-76-2 | molecular formula | C18H16FNO4S |
| molecular weight | 361.39 g/mol | Exact mass | - |
| PSA | 94.800 Ų | logp | 2.6 |
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