compound introduction
KRpep-2d is a potent K-Ras inhibitor and inhibits proliferation of K-Ras-driven cancer cells. KRpep-2d can be used for cancer research In Vitro KRpep-2d has cyclic structure with importance for K-Ras inhibitory activity. Leu 7 7 , Ile 9 and Asp 12 are critical amino acid residues for the K-Ras inhibitory activity of KRpep-2d. KRpep-2d (10-30 μM) has inhibitory activity of A427 cells with the proliferation rates of 68.3% (10 μM) and 48.3% (10 μM). MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid IC50& Target:K-RAS
