AF40431, the first reported small-molecule ligand of sortilin, has an IC 50 of 4.4 µM and a K d of 0.7 µM . AF40431 is bound in the neurotensin-binding site of sortilin Form:Solid IC50& Target:IC50: 4.4 µM (sortilin) Kd: 0.7 µM (sortilin)
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AF40431
CAS number:181125-92-8 molecular formula:C17H21NO5
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| Chinese alias | - | ||
| English alias | - | ||
| CAS number | 181125-92-8 | molecular formula | C17H21NO5 |
| molecular weight | 319.35 g/mol | Exact mass | ≥98% |
| PSA | 95.900 Ų | logp | 0.400 |
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