CAS number：6980-25-2 molecular formula：C22H22O11
Swertiajaponin is a tyrosinase inhibitor , forms multiple hydrogen bonds and hydrophobic interactions with the binding pocket of tyrosinase , with an IC 50 of 43.47 μM. Swertiajaponin also inhibits oxidative stress-mediated MAPK/MITF signaling, leading to decrease in tyrosinase protein level. Swertiajaponin suppresses melanin accumulation and exhibits strong anti-oxidative activity Form:Solid IC50& Target:IC50: 43.47 μM (tyrosinase)
| Chinese alias | 獐牙菜苷 | ||
| English alias | 2-(3,4-dihydroxyphenyl)-5-hydroxy-7-methoxy-6-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]chromen-4-one | 4H-Benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-6-beta-D-glucopyranosyl-5-hydroxy-7-methoxy- | Swertiajaponin | Leucanthosi | ||
| CAS number | 6980-25-2 | molecular formula | C22H22O11 |
| molecular weight | 462.40 g/mol | Exact mass | ≥99% |
| PSA | 186.000 Ų | logp | 0.200 |
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