compound introduction
BNN3是可透过细胞的笼状光不稳定一氧化氮（NO）供体（λ| Em（max）|：〜300nm），在氙气灯或激光照射（300-360nm）时，每分子BNN3产生两个NO分子手电筒。BNN3在大鼠主动脉条中引起光诱导的血管舒张，可用于在微秒级的时间内将一氧化氮递送到细胞内区室，而没有任何细胞毒性作用。BNN3在各种pH值水平下都是稳定的，其NO的释放不受生物系统中硫醇的存在的影响。 BNN3 is a cell-permeable, caged, photolabile nitric oxide (NO) donor (λ|Em (max)|: ~300nm) which produces two NO molecules per molecule of BNN3 upon irradiation (300-360nm) with a xenon lamp or laser flashlight. BNN3 causes photo-induced vasorelaxation in rat aortic strips and is useful for delivering nitric oxide into intracellular compartments on a microsecond time scale without any cytotoxic effects. BNN3 is stable at a variety of pH levels and its release of NO is not affected by the presence of thiols in biological systems.
