CAS number：755038-02-9 molecular formula：C28H39N7O3
BI 2536是一种有效的Plk1抑制剂，IC50为0.83 nM，比作用于Plk2和Plk3选择性分别高4和11倍。A Plk inhibitor with efficacy against 32 cancer cell lines. BI2536 is a potent Plk1 inhibitor with IC50 of 0.83 nM. It shows 4- and 11-fold greater selectivity against Plk2 and Plk3. A Plk inhibitor with efficacy against 32 cancer cell lines.
| Chinese alias | - | ||
| English alias | (R)-4-(8-cyclopentyl-7-ethyl-5-methyl-6-oxo-5,6,7,8-tetrahydropteridin-2-ylamino)-3-methoxy-N-(1-methylpiperidin-4-yl)benzamide | EN300-18167228 | (R)-4-((8-cyclopentyl-7-ethyl-5-methyl-6-oxo-5,6,7,8-tetrahydropteridin-2-yl)amino)-3-methoxy-N-(1-methylpip | ||
| CAS number | 755038-02-9 | molecular formula | C28H39N7O3 |
| molecular weight | 521.66 g/mol | Exact mass | - |
| PSA | 103.000 Ų | logp | 3.7 |
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